Jaime Caro

Adjunct Professor, Faculty of Medicine and Health Sciences, McGill University

Dr Caro is Chief Scientist at Evidera where he advances Evidera’s leadership in developing and applying novel techniques in modeling, health economics, comparative effectiveness, epidemiology, and outcomes research. Dr. Caro is also adjunct Professor of Medicine, Epidemiology and Biostatistics at McGill University, and Professor in Practice at the London School of Economics. He also lends his teaching ability to other academic institutions such as Thomas Jefferson University School of Population Health and Saw Swee Hock School of Public Health, National University of Singapore.

Dr. Caro continues to pioneer new methodologies. In an effort to provide an alternative to the well-known cost per QALY technique and avoid many of the latter’s problems, he is working on a broader approach to valuing health benefits. He is also further developing DICE, the unified approach to health economic modeling that he has created. Working with health technology assessment agencies and academic groups, he is formalizing this innovation to enable rapid, standardized and less error-prone development of decision-analytic model. On behalf of the German health technology assessment agency, he proposed an innovative approach to the assessment of health technologies, involving the efficiency frontier. As part of his work with governments, he has helped the World Bank Institute and the InterAmerican Court for Human Rights address the growing problem of Supreme Courts overriding health care system decisions and ordering them to provide treatments that had been considered unwarranted. After leading the Quality Assurance for Modeling Studies Task Force, jointly sponsored by ISPOR, Academy of Managed Care Pharmacy and the National Pharmaceutical Council, and the ISPOR-SMDM Good Modeling Practices Task Force, endorsed by the Society for Medical Decision Making, Dr. Caro was recently named co-chair of the ISPOR Science and Research Committee and has been awarded the Marilyn Dix Smith Leadership Award.

Jörgen Möller

Vice President, EVIDERA

Jörgen specializes in simulating complex systems and played a key role in simulating the re-design of the Swedish national postal distribution system, the extension of Stockholm-Arlanda Airport, and the utilization of surgical theatres at Eskilstuna Hospital. Jörgen is also an Honorary Visiting Associate Professor with the Saw Swee Hock School of Public Health, National University of Singapore.

Intrigued by the dearth of simulation in pharmacoeconomics and outcomes research, Jörgen joined Caro Research (now part of Evidera) in 2003 as a specialist in discrete event simulation (DES) and has been instrumental in implementing DES as a modeling tool in HTA. His focus has been on translating methods from operations research to pharmacoeconomics and on developing guidelines for this type of modeling. Jörgen has created more than thirty DES models in the areas of devices and pharmaceuticals. Since discretely integrated condition-event modeling was devised by Dr. J. Jaime Caro in 2016 Jörgen has been deeply involved in the development of the technical platforms for the Discretely Integrated Condition Event (DICE) simulation. He also conducts advanced training courses in DES, the ARENA-software, and DICE. Jörgen received an MSc-degree in mechanical engineering at Lund University, Sweden.

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